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Polymyalgia Rheumatica (PMR) | Last Active: 1 hour ago | Replies (74)

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@dadcue

Actemra has helped me tremendously. It was still a rocky road to finally taper myself completely off Prednisone. Depending on how long you have been on Prednisone ... it might work faster for you.

People say Actemra doesn't help with adrenal insufficiency. I would say it might not help directly but indirectly it does ... without Actemra, I would have never been able to stay on a low enough of a Prednisone dose that would allow my adrenals to recover. I had to stay on 3 mg or less of Prednisone for more than 6 months for my cortisol level to improve. I couldn't get much less than 10 mg without Actemra. Whenever I managed to get to 7 mg ... I flared and had to increase my dose again.

Actemra doesn't suppress my adrenal function so that was a huge benefit. Plus if Actemra doesn't work it can be stopped easily. It is worth a try but no guarantees. Actemra also has some side effects and it is expensive,

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Replies to "Actemra has helped me tremendously. It was still a rocky road to finally taper myself completely..."

I've been on Prednisone since the last week of July 2024. Started with 60 mg. for 6 weeks, due to suspected GCA. When I got to 8 mg. the beginning of December, I had a flare, that set me back to 13 mg. That's when I told my rheumatologist that I wanted to try Actemra.

I am aware of Actemra side effects, but I'm over dealing with the Prednisone side effects. I honestly think that, when I was having headaches, blood sugar spikes (>200) and chest pains over the past few months, it was the Prednisone. I'll take my chances with Actemra. I'm lucky that I have Medicare.