Transdermal HRT

Posted by vkmov @vkmov, Oct 19, 2023

Many studies have found that transdermal HRT protects and builds bone without all the horrific side effects of many first-line osteoporosis treatments. The patch bypasses the liver and thereby avoids the risks of breast cancer, strokes, etc. Has anyone explored this or discussed it with their doctors?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

This is all so helpful. Thank you to all! I'm 54 and diagnosed with osteoporosis end of Oct (randomly asked for DEXA at my summer physical). I'm 54 and reasonably fit, so this came as a surprise to me. I'm currently working with an endo to confirm there isn't something causing me to get osteo so "young". I've been considering HRTs since Oct (been doing a ton of research) but have been hesitant due to WHI a long time ago! Based on your comments, I'm contacting my doc today to get HRTs started.

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@patwerthman

So treating bone density with HRT?

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I have been taking meds for osteoporosis:
Forteo, alendronate, evenity and one injection of Prolia. My intention is to have one more injection of Prolia to lock in gains from evenity. I anticipate that the bhrt will enhance bone but I don't expect it to go beyond that. If it did I would be delighted but I am clear that I will need osteoporosis meds
Until I die if I don't want fractures.

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@patwerthman

Gotcha. I asked for HRT and both my primary and the endocrinologist I saw said no. Not for me. So do you take HRT exclusively or in conjunction with another med?

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I took Forteo for two years and then went on HRT to maintain the gains. I'm not currently on any other medication for my osteoporosis.

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@gravity3

I have been taking meds for osteoporosis:
Forteo, alendronate, evenity and one injection of Prolia. My intention is to have one more injection of Prolia to lock in gains from evenity. I anticipate that the bhrt will enhance bone but I don't expect it to go beyond that. If it did I would be delighted but I am clear that I will need osteoporosis meds
Until I die if I don't want fractures.

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Thank you. I hope you can stay away from fractures as well.

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@patwerthman

Gotcha. I asked for HRT and both my primary and the endocrinologist I saw said no. Not for me. So do you take HRT exclusively or in conjunction with another med?

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I have osteopenia in hips and just crossed into osteoporosis in the spine. I'm hoping the transdermal patch, currently .0375, and micronized progesterone, will help me stabilize bone loss and buy me some time before needing a bone med, or perhaps (!) help me avoid them in the future. That in conjunction with exercise, diet and supplements... Time will tell!

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@sonodeka

I have osteopenia in hips and just crossed into osteoporosis in the spine. I'm hoping the transdermal patch, currently .0375, and micronized progesterone, will help me stabilize bone loss and buy me some time before needing a bone med, or perhaps (!) help me avoid them in the future. That in conjunction with exercise, diet and supplements... Time will tell!

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Oh yes. Sounds like you are in a good plan. Crossing my fingers I can get there also

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@teb

Thank you for sharing that information. I will give it some time to see if my body adjusts. Haven't started it yet but I'm anxious to move forward.

I never mind anyone asking my age! I'm 67. Went through menopause at about 52-53. Diagnosed with osteo at 57. Refused meds, being the health conscious person that I am. Tried to build bone naturally eating a stellar diet, calculating all of my nutrition so that I met all targets, increased exercise to 2 hours a day, got a standing desk so was weight-bearing all day, blah blah blah. My next dexa 2 years later showed additional major bone loss so I knew I had to accept a pharmaceutical or I'd be in big trouble. I went on Forteo for 2 years, gained some bone back and then chose to go on HRT to maintain the gains. I was about 62-63ish at the time. That's my gory story! More info than you asked for but I share it in the hopes that it might help some others in their decision making.

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Hi teb, have you been able to maintain (or build) bone density with the HRT since going off Forteo 4 years ago? I'm 68 and was diagnosed with the beginnings of osteoporosis (-2.5). I had been on a low dose of HRT for many years but recently switched to the patch (0.5). I had a severely bad reaction to one dose of alendronate last fall so am going at this with exercise, diet, supplements, etc. all the usual. Also am hoping the patch will be more effective than the pill was. I know it's certainly safer (and I'm quite angry with all the doctors who never told me this but instead tired to get me to go off HRT completely - all women ironically). Thank you for the info. Again, wanting to know if you've had any loss since stopping Forteo. Thanks.

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