I'm sorry to hear that your cancer has recurred. That's a nasty shock.

I haven't gone into remission, but I have had carboplatin/paclitaxel twice for a total of 14 cycles, the second set of 8 with Keytruda added. I have a Grade 3 endometrial cancer, so I had chemo and radiation shortly after my hysterectomy, even though there was no cancer detectable. Then chemo plus Keytruda when it recurred, spread through my abdomen, 9 months later. I haven't had good luck with this combination, but some people definitely do make it to "no evidence of disease" status on this combination. Every cancer is different.

I think my experience on carbo/taxol was fairly typical, and I only had about 3 or 4 days of each 3 week cycle where I felt pretty bad. They load you up with long-acting anti-nausea drugs and steroids, so on the day of the infusion and the next day, I felt pretty good, though a bit sleepy. The second day after the infusion, a little less good. The third day and fourth days after the infusion were when I felt worst, and thought I would never want to look at food again. By the fifth day, I was improving, and by the sixth or seventh day, I felt pretty good again.

These drugs caused constipation for me. The first time I was on them I was trying to figure out how much Miralax to take. This didn't really speed up resolution of the problem, but made it messier when it did resolve. So the second time on chemo, I didn't worry about the constipation. It goes away in a week.

My hair started falling out exactly 2 weeks after the first infusion (both times). It makes a mess of your house, so I'd recommend shaving it off once it starts falling out in chunks.

Paclitaxel causes peripheral neuropathy. I was icing my hands and feet, but my feet are still somewhat numb. I decided that you should ice your hands and feet during the infusion and maybe for an hour afterwards, but then you should warm them up and keep them warm for a couple days. I think the numbness didn't get any worse once I started making sure to keep them warm afterwards.

I had no side effects at all from Keytruda, but then again, it didn't work on my tumor either. My impression from reading people's stories on this site is that most of the people who had side effects also had a very significant response of their tumor.

The first time I was on these drugs, I was thinking that I would do this once and it would be over. So I was really cautious and put my life on hold. The second time, I knew this was never going to end, so I went on with my life, traveled, etc.. You should see how it affects you, but you can probably live your normal life for at least the last two weeks of each three-week cycle.