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muscle weakness from blood thinners like Eliquis

Heart & Blood Health | Last Active: Oct 25 10:50am | Replies (31)

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I have been on Eliquis for 1 year and 3 months for DVT, PEs, and a saddle embolus. I have experienced fatigue and muscle weakness, but I did not associate it with Eliquis. Approximately one month ago, my dose was decreased for maintenance, and I begin to experience severe pain in my hips and legs which impaired my mobility. This occurs every morning when I get up and when I have sat too long. The pain is relieved with Acetaminophen after approximately 30 minutes and I am able to ambulate without any problems. However, I am taking Acetaminophen every 6 hours to combat the pain. I recently had an x-ray done and was told that no problem was seen. These symptoms are not listed as a side effect for Eliquis, but that does not mean it is not a side effect. I am a registered nurse with 43 years of nursing experience, and 34 years was in critical care. I personally feel this needs to be investigated to determine if there is a correlation of these symptoms with Eliquis. It will never be determined a side effect if some research is not done to rule it in or out. I am happy to discover this blog. This blog is connected to the Mayo Clinic, and maybe it will draw attention to the research department so that the issues will be looked at closer. If anyone else has these problems, please blog about it so that it can at least be looked at.

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Replies to "I have been on Eliquis for 1 year and 3 months for DVT, PEs, and a..."

Welcome @sheila64, I have been on Eliquis since having a DVT followed by a POE almost a year and a half ago. I've been on 2.5 mg twice daily for the past year. I have shoulder pain and lower back pain every day mostly in the morning but it's not from the Eliquis. Mine is due to degenerative arthritis. I have a follow up appointment with my Mayo cardiologist in April to see if I have to stay on Eliquis for the rest of my life. Actually I think there is quite a bit of research going on for the drug but I haven't dug too deeply. Here's a search on Google Scholar which is one of my favorites for finding medical research info - https://scholar.google.com/scholar.

Have you tried Google Scholar before? - https://scholar.google.com/

@sheila64 I was on 5mg, twice a day for a saddle embolism and now off it for a month and was told effects would go away in 3 days. They haven't. Odd effects seemed to happen randomly while on it. Suddenly I could not lift my left leg up to get into the car, so ended up backing into the seat. I still have some of the expected gastrointestinal effects, my walk is odd, hips, knees and shoulders affected and oddest, one side of my upper teeth suddenly moved and now overlap.also random. I had no arthritis and rarely felt pain, but now when asked for a number, it's a 10. Agree re research.