Lanus solostar side effects

Posted by cheyne @cheyne, 1 day ago

Hi,
Has anyone experienced side effects from Lantus solostar insulin. I'm just discovering some serious symptoms that have been masked and blamed on Autonomic polyneuropathy. It is making a huge difference to my ability to function although it does bring down my glucose level. I had 2 months off insulin and discovered these effects after ten days back on insulin. They have been noticed and reported previously but all had been attributed to the Autonomic polyneuropathy. I am affected by diabetic neuropathy which is manageable so far, but not having any spark to get up and do anything is debilitating. I can't lay around and do nothing but watch life pass me by. Anyone experience side effects of lantus. I researched it but can't find anything regarding elevated BP with it and can't be sure which is insulin or Autonomic polyneuropathy.
Cheers

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I took Lantus years ago. I can’t say it caused any issues. I then switched to Levemir long acting for a while. Then, to a pump where I take only fast acting. I’ve never heard of Lantus causing neuropathy or fatigue.

How is your BG now? If you had high levels, it might take a little while to start feeling better once it comes down. I have found that with steady levels in good range, I feel much better and have plenty of energy.

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I’ve had diabetes for 50ish years. I was on Lantus at some point and had really good results with it. I wasn’t aware of any side effects while using it. I was diagnosed with peripheral and autonomic neuropathy. Both were considered complications of the diabetes. It was long before being on the Lantus.
If you don’t mind me asking, what does the Autonomic Polyneuropathy consist of? My Autonomic Neuropathy was in the form of gastroparesis.
You mentioned being off of insulin for 2 months. Why was that? I’m trying to understand the timeline of your insulin use, being off insulin then back on and then your side effects appearing (as you seem to be also).
I have one other idea. (My daughter has no pancreas function. It was destroyed due to chemotherapy and immunotherapy for breast cancer. She is done with that now, had a double mastectomy and is preparing for breast reconstruction.) She is cancer free now but is on insulin. She was on Lantus but it “did not agree with her” and she was switched to a different long acting type of insulin. I can ask her in what way did it not agree with her. Maybe her experience will shed some light on your own.
Come to think of it my diabetic brother had to try a few different types of insulin before finding the right fit for him. Thank God there are options and we have providers that can help us find what works best for our particular situation.

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Hi,
There are a lot of known side effect to lantus solostar insulin. Fortunately I don't get them all, just enough to cause major problems. I'm T2 which from what I gather get more side effects to lantus than T1's do.
That was affected by diabetic neuropathy, not insulin causing neuropathy!
I get; blurred vision and struggle to read, dizziness, headaches, joints and muscles aches and pain with stiffness making it difficult to get up and move, nervousness, tiredness, sore throat with a touch of anaphylaxis, anxiety and irritability, stuffy nose, trouble concentrating, voice change goes even deeper and can lose it by the end of a day, profuse sweating, elevated blood pressure which is already elevated from the Autonomia (ANS) and chronic constipation, likely from the sweating.
The pump system is not an option through cost.
I stopped insulin yesterday and glucose is rising just passed 9 this morning heading to 18 range for the day ( European scale metric). Sitting waiting for the effects of insulin to wear off struggling to see what I'm typing.
My symptoms are covered by both lantus and Autonomia. Strange that they mostly disappear when off insulin.
My complete nervous system is compromised (ANS) with some functions being permanently damaged and other being random daily events. The Peripheral neuropathy (PN) part is up to my knee in the left leg and to my ankle with the right foot. Fortunately with compromised nerves I don't feel a lot of pain, it has to be really sharp and severe for me to feel it.
Cheers

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@cehunt57

I’ve had diabetes for 50ish years. I was on Lantus at some point and had really good results with it. I wasn’t aware of any side effects while using it. I was diagnosed with peripheral and autonomic neuropathy. Both were considered complications of the diabetes. It was long before being on the Lantus.
If you don’t mind me asking, what does the Autonomic Polyneuropathy consist of? My Autonomic Neuropathy was in the form of gastroparesis.
You mentioned being off of insulin for 2 months. Why was that? I’m trying to understand the timeline of your insulin use, being off insulin then back on and then your side effects appearing (as you seem to be also).
I have one other idea. (My daughter has no pancreas function. It was destroyed due to chemotherapy and immunotherapy for breast cancer. She is done with that now, had a double mastectomy and is preparing for breast reconstruction.) She is cancer free now but is on insulin. She was on Lantus but it “did not agree with her” and she was switched to a different long acting type of insulin. I can ask her in what way did it not agree with her. Maybe her experience will shed some light on your own.
Come to think of it my diabetic brother had to try a few different types of insulin before finding the right fit for him. Thank God there are options and we have providers that can help us find what works best for our particular situation.

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Hi,
Autonomic polyneuropathy is the Autonomic nerve system and the polyneuropathy is all the rest of the nerves. When neuropathy is used it is usually a specific neuropathy, poly is all of them. It is likely from many years of undetected diabetes and untreated high blood pressure with a serious bout of Campylobacter which almost killed me, being the icing on the cake. I have not been diagnosed with gastroparesis but then they have stopped looking as my digestive system is no longer working correctly from the Autonomia. It takes me 4 hours to digest fluid and 6 hours to digest food. If I consume more than 4 slices of bread per day and 6 cups of fluid I'm in trouble, I can manage 2 eggs as a substitute for 2 slices of bread and regularly do. Keep eating and I slip into SIBO. If I act quick enough I can stop the SIBO, but not always. I'm in a constant state of hunger and am on prescription multi vitamins. It is a difficult act to balance my diet and not satisfy the constant hunger. Fortunately I now recognise the symptoms of going into SIBO and also keep a course of antibiotics on hand just for that.
I have multiple health issues which dictate what I can and can't eat in conjunction with the digestive problems. I'm told I should eat what I can regardless if it is good for me or not. The objective being to get food into me anyway I can.
Insulin has been doing a great job for me but as we now find out that is and has come at a price.
I'm due to have the insulin reviewed next week. Oral medication has proved to be a problem which is why I was put on insulin.
I stopped insulin and my BP meds 2 months ago because I felt there was something wrong. I figured as Autonomia had a firm grasp of me what the H, throw caution to the wind and see how long I survive. I always knew I felt better off meds so gave it a whirl. Yes I do feel totally different off meds able to get on with life, get up in the morning wanting to work or do something. In the 2 months since I have been able to do all the maintainance jobs around the house that had become around to it jobs. The difference of being alive or the living dead.
I now only medicate for my digestive system which I need to or the game won't last long.
My gastrologists tell me to just do what feels right as they cannot help anymore, there being no cure or treatment for this incidious disease. I have experienced everything from temporary paralysis being unable to move from the waist down, having great difficulty walking unaided to being constipated for days, severe vertigo, tinitus and instability. I have managed to push through everything but the digestion, even survived 15 TIA's last year.
As it is now I'm undecided what I will do, but the main objective is to be as comfortable as possible.
Cheers

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There are other insulin options. If you need it to manage blood sugar levels, you could discuss options with your doctor. When you took it did you monitor your blood sugar levels? Low blood sugar can cause sweating, dizziness, weakness, etc. But, that can be resolved by consuming juice or sugar tablet. Monitoring blood sugar levels is crucial when taking insulin.

If you feel you have issues with all meds, I might explore medication anxiety. My mom has it and she believes all meds make her sick. It can be debilitating and prevent proper treatment therapies.

I certainly hope you can sort this out with treatments that works for you. Best wishes for your journey ahead. Have you considered palliative care?

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Hi,
Yes I'm aware there are other insulin options, they will be reviewed in 3 days. I can only wish I had medicine anxiety but sadly when my wife and close friend tell me I've changed again, it is not just me noticing it. In fact I'm usually the last one to notice it. Now I'm more aware of it I pick up on it sooner. There is a family trait of adverse reactions to most medications, they either don't work or they make us ill. The ones that do work without side effects are best at half strength. I seem to do better with injected meds than the oral route. I suspect a lot of it is the pills sitting in the stomach far too long with my slow digestion, but that is just my opinion. I have stopped the lantus to see if I'm correct that it is the cause. Alternatively I have just had 2 months of relatively few symptoms apart from the digestive issues. Example, a full dose of non drowsy antihistamine will knock me out with in 3 hours, guaranteed, anisthetics last twice as long with me than normal. It seems to me the older I get the more intolerant of medication I'm becoming. That could be because I'm collecting more health issues, who knows.
I have only twice gone into hypo and the glucose pills took up to 4 hours to work, generally hyper and I think I function better slightly above the recommended glucose range. The same is true of my blood pressure. Whether it is because it has been this way for over 40 years or not I don't know. One thing for sure it is better to be comfortable than worry about medicating, with Autonomic polyneuropathy each breath could be my last. I live for the moment and don't think about tomorrow untill it arrives.
It is 3 am this morning and I woke up with sore stiff joints, my eyesight is terrible and I feel like death warmed up, for sure something has a grip of me. My head is starting to ache and the nasel passage is dry and irritable, but life goes on, I'm still alive so I will deal with it waiting for a better day tomorrow.
Cheers

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