Here's my one data point for trying the 'dissolve in juice' method: the XR version that is filled with minuscule pellets does not readily dissolve in orange juice. Mild agitation didn't help. I ended up using a syringe to carefully suck up the pellets and deposit the desired amount into a graduated shot glass and then made sure I had the amount of juice needed. I will be taking the second third tomorrow morning. Perhaps by then it will have dissolved.

I'm splitting one 37.5mg capsule into three doses since I miscounted how many I had and have an appointment to get refills the day after tomorrow. I figure taking a third each day is better than taking one today and none tomorrow and taking my Friday dose early in the evening once I get the refill.

Just my one data point regarding the solubility of this in a mild acid water-based solution. It goes to show that it has resistance to dissolving immediately, which makes sense given that it is the extended release. I suspect that the dissolve in juice method was made for the original, non-extended version.

No withdrawal symptoms yet but I am within the time frame of yesterday's dose waning. Will report back if I remember on the severity of withdrawal. Hopefully will be none.