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@heavyphil

Fascinating genetics as play, right? So if you have children, what are their odds, since you carry the defective (sorry!) gene - 50%?
My understanding of this is limited, but can BRCA1/2 mutations occur on both X and Y chromosomes or just one?
The literature talks about “in males, for example…” but males have both and women have XX.

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Replies to "Fascinating genetics as play, right? So if you have children, what are their odds, since you..."

Yes 50% chance my children would get it and neither did.

If both parents have it there is a 75% chance of getting it from one parent and a 25% chance both will pass it on. If both pass it on, it is very unhealthy for the child.

It’s not tied to the X or Y chromosome it’s just something you have in your DNA.