Hello, ladies. I am also in your boat—had a partial vulvectomy 2 1/2 years ago, which did not achieve clear margins. Since then, I have been through two rounds of treatment with imiquimod, which is very irritating. So I, too, wear longer skirts or harem pants (available through Amazon) without underpants. I have found that I can wear leggings in a size or two larger, so the crotch doesn’t touch my vulva. Feels funny, but works! I strongly second the advice to get biopsies whenever recurrence is suspected. I also rely on Aquaphor to soothe my skin.