← Return to How many of our Fathers had BPH Prostate issues or Prostate Cancer

Discussion
Comment receiving replies
@jeffmarc

BRCA can’t actually skip generations, but getting no cancer with it sure can, the point I think you were trying to make. If my mother didn’t have BRCA I could not get it. But her father sure had it when he died of pancreatic cancer in his 40s. The interesting thing is my mother‘s two sisters both got breast cancer, one of them died from it, And one of the daughters died of breast cancer, But my mother never had any cancers.

I am 49% Ashkenazi, The highest risk for BRCA, It is sort of weird since my father is Swiss Italian and my other half of DNA is all from there. The 49% that I have was after five generations of family in the same city, Which means four generations had to all be Ashkenazi for me to have that high a percentage.

Prromise, who does the free genetic test, Sent out a graph showing the personal hereditary information of people that took the test.. That’s how I knew what my percentages were. One benefit of taking the test is you’ll get that as well It did take them a couple years between taking the test and sending that information.

Jump to this post


Replies to "BRCA can’t actually skip generations, but getting no cancer with it sure can, the point I..."

Fascinating genetics as play, right? So if you have children, what are their odds, since you carry the defective (sorry!) gene - 50%?
My understanding of this is limited, but can BRCA1/2 mutations occur on both X and Y chromosomes or just one?
The literature talks about “in males, for example…” but males have both and women have XX.