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Prednisone dosage split

Polymyalgia Rheumatica (PMR) | Last Active: 1 day ago | Replies (19)

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@janetilley

I always took my prednisone dose, whether split or in full, at 3-4 am. This made it easier to get out of bed pain free rather than taking it with breakfast and waiting for it to kick in. I slept through the ‘waiting’ period and get up usually at 8 am.

I’m now at 3mg and find an evening dose works best. I now usually supplement with Tylenol Arthritis at 5- 6 am so that mornings are pain free.

I know this approach has helped a few others so give it a try and see how you do. Good luck!

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Replies to "I always took my prednisone dose, whether split or in full, at 3-4 am. This made..."

@janetilley did taking it that early in the morning, I am assuming without food, not upset your stomach eventually? I have developped so much abdominal discomfort, acid reflux and heart burn, even tough I am on an acid suppressant (PPI) and make sure I take my prednisone with food and a big glass of water.
I tried splitting my dose for a while when I was at 13 mg. I did 11mg with breakfast and 2mg with supper. But my acid reflux seemed to get much worst in the evening. So I am back to full dose in the morning.