← Return to How many of our Fathers had BPH Prostate issues or Prostate Cancer

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@heavyphil

My father had a few bouts back in the day with probable prostatitis or BPH; he died at 72, however, from mesothelioma.
But my maternal grandfather died from metastatic prostate cancer at age 67, but his son (my uncle) died at 80 from Parkinsons and never had prostate issues at all; neither of his daughters (my mother and aunt) ever had breast/ovarian cancer and lived long lives, so I don’t think there’s a genetic link from them to me cancer wise.
But I think BRCA mutations can skip a generation so maybe? I’ve gotten the genetic testing kit recommended by jeffmarc but just as I was about to spit into the tube, my mouth became unusually dry. Decided to put off any insights into my corrupted DNA for another day😉

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BRCA can’t actually skip generations, but getting no cancer with it sure can, the point I think you were trying to make. If my mother didn’t have BRCA I could not get it. But her father sure had it when he died of pancreatic cancer in his 40s. The interesting thing is my mother‘s two sisters both got breast cancer, one of them died from it, And one of the daughters died of breast cancer, But my mother never had any cancers.

I am 49% Ashkenazi, The highest risk for BRCA, It is sort of weird since my father is Swiss Italian and my other half of DNA is all from there. The 49% that I have was after five generations of family in the same city, Which means four generations had to all be Ashkenazi for me to have that high a percentage.

Prromise, who does the free genetic test, Sent out a graph showing the personal hereditary information of people that took the test.. That’s how I knew what my percentages were. One benefit of taking the test is you’ll get that as well It did take them a couple years between taking the test and sending that information.