1. < Colorectal Cancer

Rectal bleeding: side effect of treatment (FOLFOX) and Vectibix?

Posted by lmhgator80 @lmhgator80, Feb 7 2:46pm

My husband countinues to have bright red recital bleeding only when wiping on/off 5 months post colon surgery to remove his tumor. No pain, happens even if he is not constipated. He can’t have another colonoscopy until after chemo treatments. He is on a blood thinner and currently doing Folfox and Vextibux. He is also having occasional nosebleeds that ENT said can be a side effect from treatment. Any thoughts? Is this expected from his treatment.

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hopenjoy2024 | @hopenjoy2024 | Feb 7 7:40pm

Be very mindful of anemia with the blood loss.

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Colleen Young, Connect Director | @colleenyoung | Feb 20 5:40pm

Folinic acid, fluorouracil and oxaliplatin (FOLFOX) can cause bruising and bleeding. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/folfox
"This is due to a drop in the number of platelets in your blood. These blood cells help the blood to clot when we cut ourselves. You may have nosebleeds or bleeding gums after brushing your teeth. Or you may have lots of tiny red spots or bruises on your arms or legs (known as petechiae). Less commonly you might also bleed from other areas of the body for other reasons. For instance, some people might notice their poo is quite dark or they might pass fresh blood."

@lmhgator80, did your husband tell his cancer team about the bleeding, both the rectal bleeding and the nosebleeds? Has it stopped?

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lmhgator80 | @lmhgator80 | Feb 20 6:21pm
In reply to @colleenyoung "Folinic acid, fluorouracil and oxaliplatin (FOLFOX) can cause bruising and bleeding. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/folfox "This is due to..." + (show)
@colleenyoung

Folinic acid, fluorouracil and oxaliplatin (FOLFOX) can cause bruising and bleeding. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/folfox
"This is due to a drop in the number of platelets in your blood. These blood cells help the blood to clot when we cut ourselves. You may have nosebleeds or bleeding gums after brushing your teeth. Or you may have lots of tiny red spots or bruises on your arms or legs (known as petechiae). Less commonly you might also bleed from other areas of the body for other reasons. For instance, some people might notice their poo is quite dark or they might pass fresh blood."

@lmhgator80, did your husband tell his cancer team about the bleeding, both the rectal bleeding and the nosebleeds? Has it stopped?

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Yes I called and they said as long as his hemoglobin was stable it was fine. The platelets did go back up this week, but now we discovered today that his WBC was low at 3.3 and he had a 100.7 temp at his visit. Only other symptom is some diarrhea. Not sure what think of this now, and they gave him Cipro as a precaution.

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