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Evenity injection site pain

Osteoporosis & Bone Health | Last Active: Feb 21 9:17pm | Replies (22)

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@spunkyspinster

I think I am five months into my monthly injections of Evenity. The first time I had stomach shots with no problems. I get a different stomach shot weekly during infusions at my cancer clinic (and had previously had Xgeva and also Prolia stomach shots for several years). The second time I got a Evenity shots they did them in the backs of my arms. That night I reached for something and realized I had a golf ball sized lump behind my right arm and a smaller one behind my left arm. It scared me because I forgot about the shots and after a failed transplant, I don't have an immune system and am open for every other kind of cancer. When I realized it was just the shot causing the lumps I had a good laugh. 😅 I had a shot behind each arm again today and this time I have a huge lump and swelling behind my left arm and a much smaller lump behind my right arm. When she gave me the shots I yelped out loud. That was a first but it really did sting. I mentioned what the RN said at the cancer clinic, that if they give the shots slowly it doesn't hurt much if at all. One shot specifically says to take several minutes to administer the shot. I don't know if that is the case with Evenity or not, but next time I will opt for my stomach with one on each side instead of using my arms. I have never requested using my arms so I am not sure why they seem to like that better ? Has anyone else had a pretty good sized lump ? I think it may just be the speed of the shot not allowing the shot liquid to be absorbed into the tissue. Last time I had the lump experience it took about a week for the lump to go down and disappear.

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Replies to "I think I am five months into my monthly injections of Evenity. The first time I..."

I had bruises and smallish lumps until there was a substitute nurse and I had none. The difference was she did the injections very, very slowly. I told the other regular nurse and that is how she did them and it was less painful afterwards. I find stomach better, just once I had big time bruising. She said she may have done the injection a little out of the area that they should be in. I find it is best to have the injection done not in line with the waistband of pants. She also lets the Evenity warm to room temperature.

Good luck!

I will be starting eventually 2/27/25 I’m worried about side effects