I am taking both Azathioprine 100mg per day and Prednizone 30 mg per day. I am in the process of tapering off prednizone and eventually hope to stop completely. Never had any pain taking the Aza. I have some physical fatigue in my legs. But I fight off the fatigue and try and exercise daily. Even got a small weight machine to strengthen my quads. I take alot of rest brakes during the day. I'm 68 male diabetic.