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Not sure what to do? ANA negative but RNP repeatedly high
Autoimmune Diseases | Last Active: 5 days ago | Replies (15)Comment receiving replies
Did you figure this out yet? I have all the exact same symptoms, including a negative ANA with elevated RNP antibodies. I also have intracranial hypertension and the feeling on top of my scalp has evolved into what seems to be very similar to a very deep fungal infection/kerion, potentially dissecting cellulitis of the scalp. Also atypical ANCA, high CRP. Waiting for rheumatology, but research is leading towards MCTD or lupus. Curious if you got anywhere.
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With atypical ANCA, high CRP and your scalp symptoms, I would recommend researching vasculitis. There are many different types, rare autoimmune diseases and a special clinic like your local university rheumatology clinic or Mayo, etc would be appropriate. I have 7 AI disorders, vasculitis being the latest to develop and because it’s rare, you need a special rheumatologist who deals with it and understands it. A dermatologist could do a skin biopsy if you have a rash or lesions on your scalp. If it’s vasculitis, topical steroids or oral Prednisone may help. Good luck and keep us posted on your progress!