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What could my doctor be overlooking? ANA 1:1280
Autoimmune Diseases | Last Active: 2 days ago | Replies (21)Comment receiving replies
I’m curious why you say you were misdiagnosed with lupus. Your labs are consistent with that since anti-dsDNA is pretty specific to lupus. Do you see an RNP in your labs. That might raise the question of mixed connective tissue disease (MCTD) a combination of lupus and another AI disease given your finger swelling and wrist pain. You should also have a SPE (serum protein electrophoresis) since IGA is high to check for MGUS, sometimes seen in other AI diseases.
Replies to "I’m curious why you say you were misdiagnosed with lupus. Your labs are consistent with that..."
Hi! I had to follow up because I went to the rheum yesterday for a follow-up. She pulled more labs:
-Beta 2 Glycoprotein 1 Antibodies IGG, IGM and IGA: IgA was high, all others normal. This was the only "positive/elevated" result I had.
-Rheumatoid factor: normal
-Cyclic Citrullinated Peptide IGG: normal
-Cardiolipin Antibodies, IGG and IGM: normal
-DSDNA: normal!
-Extractable nuclear antibodies profile: normal
-C3 and C4 complement: normal
-Comprehensive metabolic panel: normal
-Dilute Russell Viper Venom time: normal
-CBC w/ auto differential: normal
I am stumped.
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Good morning! I say I was misdiagnosed because my rheumatologist said I was misdiagnosed and that the anti-dsDNA test is equivocal. She said that patients with lupus have very high levels of anti-dsDNA.
My RNP labs have been normal.
I will request that I’m tested for SPE. I mentioned the high IGA lab to my rheum and she said it was insignificant.
I appreciate your response!