Have been on prednisone for about 2 years. However, every time my dose is lowered the pain returns and the dose goes up again. Now the rheumatologist wants me to start methotrexate but after reading side effects I am really reluctant to start it so I really can't say if it is beneficial or not. I would really like to speak to people who have taken it and what they think of it. I wanted to stay on just prednisone but doctor is reluctant to as every time the dose is lower my inflammation marked go up.