Pick your poison. Prednisone and/or a biologic. I've been on Prednisone since July 2024. Started with 60 mg day due to possible GCA. Prednisone has turned me into a diabetic. I never had previous issues with blood sugar. I have always been active, ate the right foods (mostly), and have normal weight. At one point, my BS was 275. I've lost muscle mass. I will get my bone density checked soon. I will be getting my second Actemra infusion this week. I decided for myself, that reducing eliminating Prednisone was more important than the potential side effects of Actemra. It's an individual decision.