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Prostate cancer T3b: Anyone else had radiation and what was outcome?

Prostate Cancer | Last Active: Feb 16 12:49pm | Replies (55)
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@jcarbone

I was diagnosed with Gleason 8 a year ago. No metastasized areas. Because Gleason 8 is considered aggressive I went through 45 radiation sessions. I had very few side effects. Occasional diarrhea.

I'm on ADT and will be for 2 years. I'll be 80 this year.

I also tested positive for the BRCA II mutation. Research says BRCA II in men can mean aggressive prostate cancer, which is true in my case.

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heavyphil | @heavyphil | Feb 16 7:32am

Hey Carbone, to have BRCA2 and get diagnosed at almost 80 is unreal. This mutation can strike people many decades younger so you may have BRCA2 but either some other gene which has been suppressing its expression - or a lucky horseshoe somewhere in your anatomy🧲😆
Phil

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jeffMar | @jeffmarc | Feb 16 11:26am

I got prostate cancer at 62. I’m now 77. I found out I was BRCA2 4 years ago. That explains why it keeps coming back even after surgery and radiation and many drugs. My PSA rises very quickly if drugs are reduced.

I’m only a Gleason seven (4+3), which is considered somewhat aggressive, But after being on Darolutamide For 18 months, I’ve been undetectable for the last 15.

You might want to take a look at this video which discusses cancer treatments when you’re elderly. Is aggressive treatment worth it.
https://www.urotoday.com/video-lectures/localized-prostate-cancer/video/mediaitem/4525-overtreatment-of-prostate-cancer-persists-in-men-with-limited-life-expectancy-timothy-daskivich.html

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