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Prednisone tapering

Prostate Cancer | Last Active: 3 days ago | Replies (17)

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@larryf954

The strange thing is that when I was on the ADT my hot flashes were minimally sensed. Now I feel them more frequently and stronger. So while I understand they’re associated with the reduced testosterone perhaps they are less tolerated or the sensation is more noticeable with the reduced prednisone. I’m not stating that as scientific fact; rather it’s an explanation of my circumstances as best I can account for my condition. Thank you for the reply

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Replies to "The strange thing is that when I was on the ADT my hot flashes were minimally..."

Prednisone provides cortisol for your body. If you have low cortisol, you have fatigue and from the below web information, you can also have hot flashes. It would be interesting to see what your cortisol test results are. It sure sounds like you should be on a little bit more prednisone. Talk to your doctor about this, The below information sure seems to tell you that it’s too little prednisone.

From the web
A lack of cortisol can potentially contribute to hot flashes, as low cortisol levels can disrupt the body's hormonal balance and impact the brain's temperature regulation, leading to hot flashes even when estrogen levels are not significantly low; this phenomenon is sometimes referred to as "stress-induced hot flashes" due to cortisol's role as a stress hormone

Larry, I was on Orgovyx for 6 months only - no prednisone. I’ve been off of it for only 2 weeks but my hot flashes have increased in number and intensity. I never broke into a sweat the whole time on Orgovyx; now I have to pull off my shirt when I get a flash.
Bloodwork in a month so we’ll see what that says…
Phil