Vitamin D Not Responding to Supplementation- Seeking Insights

Posted by chaiyosef @chaiyosef, Feb 12 6:26am

I’m a healthy 46-year-old dealing with persistent insufficient vitamin D levels despite increasing supplementation over the past year, and I’m hoping to hear from others with similar experiences. For several months now, I’ve been taking 40,000 IU of Vitamin D3 per week, but my levels are still not going up.

Additional concerns:
• I have osteoporosis, so getting my vitamin D levels up is crucial before starting treatment.
• My PTH (parathyroid hormone) has been mildly elevated at times, but my specialist does not believe it’s a major factor.
• My cholesterol has significantly increased despite no dietary changes, and I wonder if there’s a connection.
• I maintain a balanced diet, including dairy and other calcium sources, and exercise regularly, including weight-bearing activities.

Has anyone here experienced vitamin D resistance or poor absorption?
Did you find any underlying cause (gut issues, genetic factors, or something else)?
What strategies have worked for you?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

chaiyosef -- I am going to get the dummy award in this conversation, but have you tried sunlight?

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This may have nothing to do with it, but I had a GI Map done by Dr McCormack and my gut was off so he gave me some advice about that and I didn’t have enough hydrochloric acid to digest what I eat. I now take Digestymes. This may have nothing to do with your issue, but it probably wouldn't hurt to try a bottle. I get it on Amazon.

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@kallettla

This may have nothing to do with it, but I had a GI Map done by Dr McCormack and my gut was off so he gave me some advice about that and I didn’t have enough hydrochloric acid to digest what I eat. I now take Digestymes. This may have nothing to do with your issue, but it probably wouldn't hurt to try a bottle. I get it on Amazon.

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I am interested in the GI Map done by Dr McCormack. I did not think chiropractors could order medical tests except as related to chiropracty.

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@normahorn

I am interested in the GI Map done by Dr McCormack. I did not think chiropractors could order medical tests except as related to chiropracty.

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He did it for me! It was very interesting. He has a web page and practices in Belchertown, MA. I live in MA. I don’t know if he can only practice on MA residents. Certainly get ahold of him.

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@kallettla

He did it for me! It was very interesting. He has a web page and practices in Belchertown, MA. I live in MA. I don’t know if he can only practice on MA residents. Certainly get ahold of him.

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I prefer to avoid people who practice medicine without a license.

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I can understand, however in this case he is the middleman. He orders the test and it goes directly to the company whose Dr's read and interpretate it and let Dr McCormack know what I can do to reverse the issues. I do feel much better now. I had extremely high ecoli, a gluten sensitivity , and an issue digesting the food I ate. Perhaps, you can find a company with a good reputation and work with them directly.

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There are different Vit Ds. Sounds like you need a prescription for Ergocalciferol or Calcitriol.
OTC Vit D did not work for me. My endo then ordered the ergocalcifierol which also didn't work and then put me on calcitriol and that elevated my Vit D plasma levels. I had been on calcitriol 0.25 mcg 4 days a week and 0.5mcg 3 days a week calcitriol. I stopped everything when I went on Tymlos. My Vit d level is now 15 which is low and I expect that I will be put back on calcitriol this week.

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@zygote

There are different Vit Ds. Sounds like you need a prescription for Ergocalciferol or Calcitriol.
OTC Vit D did not work for me. My endo then ordered the ergocalcifierol which also didn't work and then put me on calcitriol and that elevated my Vit D plasma levels. I had been on calcitriol 0.25 mcg 4 days a week and 0.5mcg 3 days a week calcitriol. I stopped everything when I went on Tymlos. My Vit d level is now 15 which is low and I expect that I will be put back on calcitriol this week.

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Thank you for sharing your experience. It’s really helpful to hear how your doctor approached your vitamin D treatment, especially with the different forms. I hope your levels improve now that you’re restarting calcitriol. Wishing you the best with your treatment and overall health.

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