Connect
← Return to Gordonia bronchialis
Discussion
Comment receiving replies
@tcd518
This is a quite rare finding, and usually occurs after something like open heart surgery. Here is a summary/compilation of several years of reports:
The results of our study showed that G. bronchialis causes numerous, diverse, and serious infections encompassing pneumonia and osteomyelitis as the most frequent, followed by bacteremia, endocarditis, and peritonitis, etc. Human samples for the isolation of G. bronchialis were collected from sputum, wound tissue, blood, bone, peritoneal and pleural fluid, corpus vitreum, and medical device (pacemaker), while its identification was confirmed using gene sequencing method and/or MALDI-TOF-MS analysis. Sensitivity to antibiotics, such as ciprofloxacin, imipenem, and amikacin was proven in the largest number of cases. Treatment of infection caused by G. bronchialis was primarily based on combined antibiotic therapy, while one anti-infective drug was administered in two patients. The most frequently used antibiotics were vancomycin and ciprofloxacin. All patients underwent hospital treatment and recovered completely after therapy (one without treatment)...
Overall, infections due to G. bronchialis were most often represented among patients associated with cardiac surgical intervention (usually coronary artery bypass grafting) and/or the implantation of prosthetic materials (cardiac pacemaker, indwelling catheters, prosthetic valve, intraocular lens implant, and bioresorbable polymer screw). Out of a total of 28 patients included in our systematic review, only two patients did not undergo surgery or insertion of prosthetic material. No data were available for five patients.
Treatment of infections caused by G. bronchialis was mandatory based on pharmacotherapy in all patients, except one.
A review of the literature related to G. bronchialis infections in humans, clearly shows the difficulties associated with its identification, even today. Gordonia bronchialis was often misidentified as Nocardia, Rhodococcus, or non-tuberculosis mycobacteria...
Gordonia bronchialis infections should be taken seriously, because if not, it can lead to a high degree of resistance to antibiotics. The treatment of G. bronchialis infections should include fluoroquinolones, vancomycin with or without aminoglycosides, and carbapenems. Cotrimoxazole as well as linezolid should be avoided, because in some cases G. bronchialis shows resistance to those antibiotics."
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1333663/full
I would guess your provider iss going to order antibiotic therapy - have you spoken to them yet?
Replies to "@tcd518 This is a quite rare finding, and usually occurs after something like open heart surgery...."
Connect
Hi Sue. No, I haven't spoken to the doctor yet and probably won't until next week because of the holiday. This test result is from one of three sputum samples submitted at the beginning of January; the first sample was negative, the second showed the Gordonia, and the third showed MAC. I can't help but wonder if there's a lab issue here. I haven't had any kind of surgery or invasive medical treatment, just a persistent, wracking cough.
The irony is that I just started the Big 3. Last week I began with 500 mg azithromycin, next week I add 1500mg ethambutol, and the following week I add 600 mg rifampin, all three times a week (Monday, Wednesday, and Friday). Now I wonder if that will change.
Thank you so much for this information. It is very helpful to me and gives me some background when I talk to the doctor. Stay well.