Hi, @petrullo - welcome to Mayo Clinic Connect. Sounds like you are having some challenges with your taper off prednisone and perhaps with the drug itself.

I have taken 2 tablets of 20 mg of prednisone daily for 5 days when I have an asthma flare I cannot get resolved. It seems to resolve the flare. The "cost" for me is only sleeping about 4 hours per night while on the prednisone. Also, my husband and children think it takes away the filter for my mouth. In other words, when I take prednisone, I tend to say whatever comes into my brain without stopping to think about whether it's wise, helpful, kind or a bit too "colorful."

I go off the prednisone with no taper, and I've not noticed side effects. It seems everyone metabolizes drugs differently, though. Many Connect members have reported having a tough time tapering off of prednisone.

Will you share more about what your doctor put you on prednisone for, petrullo? Did it help with the symptoms you were experiencing at all?