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Why don’t anxiety meds work for me?

Depression & Anxiety | Last Active: Sep 25 8:22pm | Replies (304)

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Thank you so much for your response. I currently am not on any medication. My last provider said she would no longer treat me if what she prescribed (Zoloft and Gabapentin) did not work for me. Well, they didn’t. I had weird brain/head sensations from one of them. I was also prescribed Buspar from another provider but I was allergic to it. I just retried Effexor 37.5 xr, but it just increased my anxiety. It has been a repeat cycle of going on a drug and a few days later, coming off of it due to intolerable side effects. I feel pretty hopeless. I have been reluctant to take Ativan which has been prescribed by my PCP for my anxiety as I know I will wind up taking too many, so I am suffering with no relief in sight. I have a very stressful situation at home as my husband has Parkinson’s Disease and instead of me taking care of him, he has to take care of me.

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Replies to "Thank you so much for your response. I currently am not on any medication. My last..."

I feel for you. I am in the same boat and I even had the genesight testing done. We have tried 2 of the meds that were in the green but could not do the side effects. Before that I had tried so many. I do take Clonazepam 1/2 pill twice a day for anxiety right now. I have lots of health issues and that causes the depression/anxiety because I have yet to find the right treatment plans. It really is a horrible place to be in. Hope you find something to help soon.

I am in the exact same boat as you are as nothing works for me. Ativan a.k.a. lorazepam does work for me, but we’re a normal human has to take one and they sleep for two days. I need Three to just calm down enough to where I don’t look like a manic all the time. And when it comes to sleep and I can’t sleep due to insomnia, they won’t give me Ambien or a Xanax so they give me like 12 different meds that they act like are wonderful and work for everyone and when it doesn’t work for me, they look at me and basically accuse me of lying. So then the bottom line comes to the only way you can get relief is to buy what you need on the street. I have literally taken 150 mg of trazodone along with 150 mg of diphenhydramine, which is in sleep medication along with my regular meds and still been up for well over 30 hours and ready to paint the house. And when I am honest with my doctors, which is all the time they just get mad and like you said with you, they canceled me. I asked one of my psychiatrist a few years ago why she wouldn’t allow me to at least try these other meds to rule them out or what not and she couldn’t give me a reason so then I asked her if she was getting kickbacks and three days later, I got a letter in the mail saying that I was canceled. Oh and I did get the genetic marking test done and it’s a company called Gen0mind. That when I had it done, it was upwards of $5000. Hopefully if you get it done it’ll be covered by insurance. Insurance usually sees it as something that is not dire so they don’t pay for it. But on a good note when I got my testing back, it did make me feel a lot better because the doctors on the phone told my doctor that like 90% of the world that gets the testing done has normal results easy to read you need more of this medication you need less of this medication yada yada yada But with me and almost every single medication on there from Tylenol to benzos to pain meds one medication I would need more of half of that medication unless of the other half of that medication!! Crazy right?!? Because you can’t take something like well. I can’t think of an example but you can’t take one medication that’s in one pill form or capsule and somehow be able to split up the ingredients so that I can take more of part of it and less of the other part. That test actually helped me a lot because when I found my newest psychiatrist one of the first things I did was send her a copy of that and also since I’m a redhead, I keep the little card that they gave me in my wallet in case I have an accident because under anesthesia, any anesthesiologist worth their salts, know that any redhead is going to need way more anesthesia than a normal person. Anyway, I hope you get the testing done and I hope you find something that works. Oh and I don’t know if this is part of your problem, but I have ADHD and OCD and because of those diagnoses things affect me back backwards. GOOD LUCK AND GOD SPEED!!

@dorothy1914 it really sounds like you need a better doctor! A doctor who refuses to keep treating you if the first thing they tried didn’t work is not a good Dr, and a Dr who has a patient cycle on and off psych meds every few days is being really irresponsible and ignorant.

Your doctor should have advised you that startup side effects from these medications are common and while they can be very unpleasant, experiencing them when you first start does NOT mean your experience with the med will always be like that. They should’ve encouraged you to stick it out past at least a week unless the side effects were dangerous or completely unbearable. And they should’ve told you that you’d likely not start experiencing positive effects right away.

A few days is WAY too soon to know whether most of these meds will or won’t work. Some can take 1-2 months to really start showing benefit! So I can’t fathom why they were having you stop/switch after only a few days.

The first week on Zoloft was awful for me. I had terrible insomnia, migraines, brain fog, brain fog, brain fog “zaps” (those weird head sensations you described, they’re very common) for the first few days but these side effects were gone by the end of the first week (maybe sooner, can’t recall). But it still took about a month or so for the meds to start helping.