I would say you should try another one. MTX has not been as successful and takes a few months to start working. Kevzara and Actemra both seem to work really good for some and not for others. Dadcue posted a QA from Dr Megan recently where she suggests to keep trying. Lufudamide(sp)? LPN? One of them may work and will eventually be better for you than long term prednisone. Her comment was that statistically speaking prednisone has more long lasting effects than any other drug. good luck.