you said
"It can be slowed with some treatment, maybe including backing off on the fruit. Fruit has a lot of fructose, and it's a demanding conversion for the liver to change it to glucose, which spikes insulin levels. High serum sugar levels cause damage to the endothelial lining of arteries due to inflammation, and inflamed tissues are a better surface for cholesterol to adhere to.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8267750/"
The article you reference is based on fructose sugar from soft drinks.
and I quote "The alarming increase in metabolic syndrome and comorbidities can only be attenuated if the consumption of fructose, mainly in soft beverages, is significantly reduced worldwide"
Fructose from whole fruit it metabolized very differently that fructose sugar used in soft drinks and does not represent the threat you imply that whole fruit fructose is = to fructose added to soft drinks.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6247175/
Food sources of fructose-containing sugars and glycaemic control: systematic review and meta-analysis of controlled intervention studies
"Energy control and food source appear to mediate the effect of fructose-containing sugars on glycaemic control. Although most food sources of these sugars (especially fruit) do not have a harmful effect in energy matched substitutions with other macronutrients, several food sources of fructose-containing sugars (especially sugars-sweetened beverages) adding excess energy to diets have harmful effects. However, certainty in these estimates is low, and more high quality randomised controlled trials are needed."