@coloradogirl I've tried to get off Effexor Immediate Release twice this past year: both times a failure! At first I tried to cut the 37.5mg tablet in half and take 18.75mg per day. This brought on really bad withdrawal symptoms (mainly psychological/emotional) for weeks. I went back to 37.5mg and got a new prescription for 25mg. This wasn't as bad but it didn't go well, and so I went back to 37.5mg after one month. It seems that no matter how long I give it, the withdrawal symptoms still seem to affect me badly. My new strategy is getting a compounded liquid solution prescription from a local pharmacy. They're willing to concoct this for me to try. I don't know though…I just don't want to put myself through this chaos again! I know you've already offered your suggestions, but would you have anything more to add in my case?