← Return to Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)

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@texasduchess

@neros
@kbmayo
@youngsally
I am so glad that your withdrawals were not that bad, or at least tolerable. Harvard physician Joseph Glenmullen, MD, writes, “78 percent stopping Effexor (venlafaxine) have withdrawal reactions ....” A survey by the manufacturer of Effexor shows that at least 35% of patients experience antidepressant withdrawal symptoms when they stop taking Effexor. (Note: Adverse reactions can be minimized by tapering off the drug. Stopping cold turkey can be very dangerous--to the point of life-threatening.)

Unfortunately, you can't tell before you start the quitting process if you're going to be one of the lucky ones to not be too bothered by withdrawal. I tapered off very slowly from only 25mg. I was fine for 6.5 weeks afterwards. Then, I started having all the withdrawal symptoms including akathisia; I think it took that long for my body to find and use up all the Effexor stored in my adipose tissues (fat). It is now six months after my last minimal dose of Effexor and I still have issues. If I had known that I'd be in for such a long haul towards recovery, I'd have stayed on Effexor even though my hot flashes were well passed. I told my doctor, "My husband and I have been married 38 years. In sickness and in health. In money, or without. But, I am not too sure about through Effexor withdrawal."

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Replies to "@neros @kbmayo @youngsally I am so glad that your withdrawals were not that bad, or at..."

I can't get off Effexor on my own. I'm 120 pounds, taking 150 mg/day. I've been taking 75 mg day 4 a few weeks, but now the rages are back. Serious rages. Homicidal rages. So had to go back up to 150 mg. I need to switch doctors to switch meds.

You are absolutely right - one doesn't know how they will be affected by a taper...and it is not knowing when the symptoms will stop that is completely exasperating. It's really awful that you are still experiencing problems six months out...but hopefully for you (and your husband) things will settle down over time. A number of people suggest a prozac bridge....have you spoken to your MD about that? In my case I am taking a low (5mg) dose of lexapro - but that is because my depression symptoms are not gone - but the effexor wasn't helping. It's only been a week, but the lexapro has tamped down some of the negative side effects of the effexor withdrawal (or I've been fortunate enough to get through the effexor stuff).