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Conolidine experiences, advice

Posted by woody6660 @woody6660, Aug 1, 2024

Hi I’m interested in conolidine experiences The good and bad mostly for pain. I have nerve and joint issues

Interested in more discussions like this? Go to the Chronic Pain Support Group.

zincisgood123 | @zincisgood123 | Dec 3, 2024
In reply to @mmalone1804 "I’m asking about the liquid form. How long did it take to feel relief at 1ml..." + (show)
@mmalone1804

I’m asking about the liquid form. How long did it take to feel relief at 1ml per day? Can you take more, or use as needed?
Thank you ahead for sharing the information.

Jump to this post

I just took my first droplets of conolidine and it seems to have reduced my pain. I am recovered from hip surgery. Stay tuned.

REPLY
1 reply
abeachgal | @abeachgal | Jan 28 7:59am
In reply to @jetsetter081268 "i have taken in liquid and used the balm both work for me. The liquid is..." + (show)
@jetsetter081268

i have taken in liquid and used the balm both work for me.
The liquid is stronger than the balm as it contains PED...

Quite a few companies sell the product under different names.
I use proleviate dropper 1ml per day has around 30 drops for the month.

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Could you divulge the company you used for the droplet that contain this PED? Thank you

REPLY
abeachgal | @abeachgal | Jan 28 8:01am

I see you mention the balm in other comments. Is it still helping? Can you share the website for the drops you bought from? There are so many out there I’m seeing some are fake on Amazon.

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abeachgal | @abeachgal | Jan 28 8:04am
In reply to @zincisgood123 "I just took my first droplets of conolidine and it seems to have reduced my pain...." + (show)
@zincisgood123

I just took my first droplets of conolidine and it seems to have reduced my pain. I am recovered from hip surgery. Stay tuned.

Jump to this post

Thats awesome! Is it still working? Can you share the website you bought from? There are so many out there I’m seeing some are fake on Amazon.

REPLY
mydeuxcentz | @mydeuxcentz | Feb 10 10:48am
In reply to @jetsetter081268 "i have taken in liquid and used the balm both work for me. The liquid is..." + (show)
@jetsetter081268

i have taken in liquid and used the balm both work for me.
The liquid is stronger than the balm as it contains PED...

Quite a few companies sell the product under different names.
I use proleviate dropper 1ml per day has around 30 drops for the month.

Jump to this post

Can you please share where others can obtain this medication? Thank you.

REPLY
Moderator
Justin McClanahan, Moderator | @JustinMcClanahan | Feb 12 10:07am

Hello @woody6660, have you had a chance to read through some of the research on conolidine? Studies are still ongoing and more research needs to be done, but early studies from 2021 showed some promise:

"Research on conolidine is limited, but the few studies currently available show that the drug holds promise as a possible opiate-like therapeutic for chronic pain."
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8908788/

"Presently, conolidine has been shown to inhibit Cav2.2 calcium channels and increase the availability of endogenous opioid peptides by binding to a recently identified opioid scavenger ACKR3. Although the identification of conolidine as a potential novel analgesic agent provides an additional avenue to address the opioid crisis and manage CNCP, further studies are necessary to understand its mechanism of action and utility and efficacy in managing CNCP."

This is all to say that there are potential benefits, but the risks and long-term efficacy have not yet been completely researched. Have you had a chance to talk about this treatment with your provider?

REPLY
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