Sue, thank you for this helpful and science based information. I am sorry you struggle with asthma and COPD. That is hard.
My son's severe asthma turned out to be non-celiac gluten intolerance. Off gluten/dairy and a couple of other foods, he has no asthma and is well. Unfortunately, this is often missed.
Two types of tests were valuable. One is a blood test for IgG (not allergy IgE) gluten/gliadin. The other is a stool test for IgA gluten/gliadin. (We also did similar testing for dairy and eggs.)
It feels criminal that these tests aren't regularly used on asthma patients. Instead, allergy IgE testing is done. That was not only unhelpful, but misleading for us.
On our long journey we were told that my son's very high IgG gluten/gliadin blood result didn't mean anything - "He didn't have celiac." Here is my thinking: While he may not have had celiac yet, the blood antibodies have significant meaning. It seems so obvious to me that we shouldn't have high levels of these antibodies to food proteins in our blood because high levels of food proteins shouldn't be in our blood. They should have been broken down into amino acids and then absorbed. Why they trigger asthma in some, skin problems or migraines or villi damage or anxiety/agitation/depression, in others, is unclear to me.
Hope you find the root cause and heal. Again, thank you.
@maryannl, same thing happened to me 30 years ago: severe uncontrollable asthma, multiple trips to e.r., no one ever tested me for gluten intolerance. One day, my 10 years old daughter told me she noticed I always have problems breathing after eating baguette and cereals, I paid attention to what she said, she was right. I went on a gluten free diet, and the severe asthma was gone.
Frustrating that doctors are not trained to test for that.
Best wishes of great health to all of us!