@sbsbtheplumber1 with so many chronic conditions and medications, hopefully your neurologist will be able to figure it out. I am a licensed behavioral health clinician and any of those meds alone can cause the symptoms you mention, especially as we get older and metabolize them differently. My husband also recently had a spinal fusion and within 24 hours the hydrocodone had him in such an altered status of confusion and inability to control his body that I had to call 911. That combined with a post surgery muscle relaxer- it was like he was on “ roofies.” He could hear me, but couldn’t make his body respond. I hope you get some answers and relief soon.