Thanks for replying, I have perhaps been using it for nearly 25 year and YES your caveat is spot on my neurologist said be careful on using it ( I used it for GI and was prescribed by a GI MD) I did not want to give it up because sometimes is the only thing that will take care of the stomach pain. I go through the routine of Tums before. My GI MD since 2017 has encouraged me to use Omeprozole (sp) on a regular basis but I have heard that too has its negative long term consequences. So I Every other day take the Omeprazole (instead of every day), when stomach pain flairs up Tums first, then Reglan after if pain doesn't go away or if too severe. Sometimes Reglan is first - and I am not talking acid indigestion, that is easy this is pain. It was neurologist ( I have epilepsy) that told me to be careful so thank you for your heads up my 90 day supply of Reglan usually is still around 2-3 years and then I replace it to have a fresher Rx :} Leslie