← Return to The lowest effective dose, how is it defined?

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Start dose was 15mg in May 2023. 10mths ago after reducing to 6.5/6mg I had my first and only flare, which only settled after going back to 15mg and reducing again. Now reducing to 5.5mg without issue, and I'm hoping not to add more medications with new problems and side effects.

Everyone is different, from dose needed to how long it takes the PMR to resolve, and which medications can be tolerated. I'm on blood thinners for thrombosis, have had heart issues and have latent tuberculosis which means some medications used for PMR can't be taken.

Let us know how you get on with the sulfasalazine. Your experience with it will be of interest to others.

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Replies to "Start dose was 15mg in May 2023. 10mths ago after reducing to 6.5/6mg I had my..."

Thank you, and yes will keep you updated. Just starting a lower dose of the prednisone today for a mth, was 10 now 7.5 (I think I mentioned this ) will keep this dose for another month, and have increased the sulfasalazine to 4 a day , we can only try can’t we. I saw a post re a Dr Megan who has a supplement for people on prednisone, have you heard of this? I’m in Australia so will see if they ship to here 🤔

Yes, I agree that everyone is different and slow taper is less likely to encounter flares. I started at 10 mg, which is low but worked for me. I am a small woman in otherwise excellent health. The rheumatologist let me choose my taper and I only had two small flares, my back at 1.5 mg and my knee at .5 mg. But I kept to the program and did not go up and they resolved themselves after a few days. I have been prednisone free for a month now with no issues. Fingers crossed!

Thanks Megz for sharing all your knowledge. My experience in PMR kind of mirrors yours. After starting prednisone at 10 mg I can’t seem to get any lower than 7. I have flared twice and the second time I was out 8 weeks on 8 mg. I am increasing tomorrow back up to 8 mg to try to give some relief from the stiffness and pain. My Rheumatologist told me just to stay on the 8 mg for awhile and try to taper later. He has mentioned Kevzara but I want to keep trying prednisone tapering if I could do it correctly. Would you have any recommendations on my taper going forward?