Hi jacquejwal, maybe there are enzymes and then there are enzymes. (1) Intoleran sell sample dietary packs for $5, so you can see if their products help you; maybe it depends on the brand. There are so many out there and they all seem to use weird units of measure; Intoleran, on the other hand, use standard units of measure. I can't live without them and I have IBS-C. (2) Have you checked out FODMAPs as an issue? Everyone is different, but I used Monash University's FODMAP app. I can eat only some "green light" low FODMAP foods. No grains at all. Limited quantities of most things. What I can count on is green plantain flour, egg whites and Lactaid milk. There must be some things you can count on too. Also, many get mileage from seeing functional MDs, though I have never gone to one.