I have posted frequently on the technique of cold therapy for the prevention of chemo induced peripheral neuropathy. The technique got its start in the colorectal cancer space about 8 years ago after being widely mentioned on the Colontown FaceBook group. From there it moved into breast cancer treatment and within the last few years for pancreatic cancer. It is most effective when started with the first cycle of chemotherapy before platin agents or taxane shave a chance to damage peripheral nerve endings. The last link is to neoprene booties and mitts with cooling gel inserts making the technique easier to tolerate of the 90 minute infusion of oxaliplatin or Abraxane.

NEUROPATHY PREVENTION WHEN TAKING FOLFIRINOX/ICING

LetsWinPC.org feature story on cold therapy
https://letswinpc.org/disease-management/ice-prevent-neuropathy/
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https://www.uspharmacist.com/article/ice-chips-prevent-hyperalgesia-with-oxaliplatin
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7810270/
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https://learn.colontown.org/topic/managing-neuropathy-and-cold-sensitivity/
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https://ascopubs.org/doi/abs/10.1200/JCO.2020.38.15_suppl.e16140
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https://paltown.org/icing/
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https://letswinpc.org/research/more-research-needed-for-neuropathy/
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https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-cold-cap-therapy-can-reduce-hair-loss-caused-by-chemotherapy/
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Link to booties and mitts for cold therapy. https://a.co/d/ipJy8Hq
Two sets of booties/mitts are necessary for the cold to last through the infusion cycle.