I have PMR and Smoldering Myeloma. My immune system has been raging for several weeks now. Several SM tests have elevated. As my Penn Med oncologist said this a.m., it's a chicken and egg situation as to causes. He talked with my rheumatologist this am. after I talked with him and they want to try Kevzara to reduce my Prednisone dependency. I'm currently on 7 mg, trying to reduce 1 mg monthly.