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Anyone seen research on long term Proton Pump Inhibitor use and PN?

Neuropathy | Last Active: Feb 4 8:39am | Replies (22)
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@maximas

I have been on Lansoprazole for +5years and now have pins and needles on hands and feet - interested to know the evidence linking PPI with this condition?

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Replies to "I have been on Lansoprazole for +5years and now have pins and needles on hands and..."
John, Volunteer Mentor | @johnbishop | Feb 3 6:50am

Welcome @maximas, Sorry to hear you are having pins and needles neuropathy symptoms in your hands and feet. There is some evidence that PPIs can cause the symptoms. Here's one of many references.
-- How can proton pump inhibitors damage central and peripheral nervous systems?
https://pmc.ncbi.nlm.nih.gov/articles/PMC7716020/
There is another discussion on the topic that you might find helpful to connect with others that share the same symptoms from PPIs.
-- Neuropathy + Proton-pump Inhibitor use?? Anyone had this experience?
https://connect.mayoclinic.org/discussion/neuropathy-and-ppi-use-has-anyone-had-this-experience/
Have you discussed the symptoms with your doctor or care team to see if there might be some alternatives?

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