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Can anyone share their experience with Pluvicto?

Prostate Cancer | Last Active: 22 hours ago | Replies (117)

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@smc24

I need to correct @jeffmarc's comment. Pluvicto is a targeted therapy that binds to prostate-specific membrane antigen (PSMA), a protein found on prostate cancer cells.
Once bound, the radioactive component of Pluvicto releases radiation that kills the cancer cells, specially lutetium 177Lu, a highly radioactive compound. The treatment delivers gamma radiation that escapes your body and can reach others around you, especially within the first 3 days after each treatment.
I had a full 6 treatments of Pluvicto in 2021-22 as a clinical trial patient for Novartis Pharmaceutical. It was approved in the US shortly afterwards. In mid 2024, my cancer became active, again and I am one a just a handful of patients anywhere in the world repeating the 6 treatment program, completely at my own risk.
I've had numerous targeted beam radiation treatments including the prostate bed and countless PET CT scans and a recent SPECT scan. And, full chemo twice. Yes, lots of radiation. If you have reached the point of receiving Pluvicto, the LEAST of your concerns should be your life radiation accumulation. Yes, too much radiation can effect bone marrow and cause other issues, but those choices might already be out of your necessary, and life saving decision making moving forward. I'm 73, battling cancer for 10 years and so far, I'm doing remarkable well with none of the excessive radiation side effects. Good luck. Don't give up, do what you have to do.

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Replies to "I need to correct @jeffmarc's comment. Pluvicto is a targeted therapy that binds to prostate-specific membrane..."

What’s is missed here is there is a major difference between the radiation you get from something liked Pluvicto and getting the maximum radiation from prostate bed treatment.

It is just not affecting the body of the same as getting more radiation to the prostate bed After having the maximum.

My husband is starting Pluvicto soon and do you have any suggestions regarding diet and anything else to get him through it? I have also asked for resources to educate myself on how much I should worry about the exposure at my age of 81/ Thanks so much and sending love, light and healing ,Lynne

smc24,
I completed my 6th Pluvicto treatment Feb-24 and PSA was .2 until Dec 24 now PSA at 3.
Have contacted my MO for re-treatment of Pluvicto, but not covered by insurance; can you advise me best way to get another 6 treatments.
Best to you