Folfirinox was really tough on my husband - fatigue, significant weight loss and generally no energy for anything. He only did it for 3 sessions (once a fortnight) and I take my hat off to your husband for doing it for 6 months! My husband could not walk 100 yards much less the mile your husband did! Because CA19-9 numbers did not come down, oncologist switched my husband to Gem-Abraxane quite quickly. Side effects much more tolerable. First it was 3 weeks on and 1 week off, then it became fortnightly with the occasional 3-weekly to allow us to travel. Hoping that it will be the same for your husband. If your husband responds well, you may not be dreaming of walks. By the 6th month of Gem-Abraxane, my husband and I were doing daily walks of just under a mile. Caregiver's job is to do the nagging, the prodding, the encouraging, and the being hopeful.