Thanks for the responses. Sorry for the delay in reading these messages and getting back. Here's an update: they did an ESD on the 27th of January. Only about 75% of the tumour was removed becasue there was severe bleeding from the varices that I had (from an old liver issue). They put a stent and had to withdraw. They plan to do an endoscopy on Wednesday, 5th February to assess and then take a call on the next steps.

I am from India. Too bad I missed the call with the Mayo surgeon.

The doctors say they will decide if attempting to remove the remaining 25% of the tumour would be safe or they should opt for some chemo to try and clear out the remaining.

I got tested for Mismatch Repair protein status in the biopsied tissue. It came back negative. They plan to test for PLD-1 and TMB apart from HER2/Neu. Are these tests that will help determine if Immunotherapy will have a better chance to work?

Thanks for responding to my questions!