@mimi1234 It sounds to me like you are in really good shape. “…no diabetes, no high blood pressure. Creatinine normal.” An eGFR of 54 is pretty good. There are often no symptoms of Chronic Kidney Disease (CKD) until the eGFR gets down into the 30’s. Many Drs consider it as mild or moderate dysfunction when it is in the 40’s and don’t prescribe any treatment until it is much lower. Do you have a nephrologist? What does he or she think?