Hi @harveyandshari, a few members have talked about Lonsurf (trifluridine and tipiracil) in the Colorectal Cancer group here:
- Lonsurf (trifluridine/tipiracil) effectiveness
https://connect.mayoclinic.org/discussion/lonsurf-effectiveness/
Researchers have found that Lonsurf selectively kills cancer cells with mutations in the TP53 gene. Such mutations are found in more than half of all cancers, including most colorectal and pancreatic cancers.

Will you be starting treatment with Lonsurf for pancreatic cancer? Are you part of a clinical trial?