How often are the infusions? Hand veins only last so long usually and bruising or swelling are easily seen. Ice helps the swelling. Cannulas or fistulas are usually only for dialysis patients. I used to be a phlebotomist. Hard draws are not fun and hurting people trying to snake into a vein is stressful for everyone involved. What then to do about anxiety for infusions. Usually in infusion centers the staff are top notch. They too understand or should what your going through. Anxiety and needles go hand in hand. A port is ok if your infusion is weekly or every other day. There are down sides as well so you have to weigh your options. Pre medication of a calming or something to relax you maybe beneficial. Also do they draw blood before infusion? Draw it from the IV line? Heating packs help too. But I’m more into what helps you with anxiety in dealing with this.