← Return to Looking for input on 2nd opinion after 3 years of Alendronate
DiscussionLooking for input on 2nd opinion after 3 years of Alendronate
Osteoporosis & Bone Health | Last Active: Jan 31 12:13pm | Replies (29)Comment receiving replies
Replies to "I have been on alendronate sodium 70 mg for 10 years. My doctor said it did..."
Dear ekarasoulis59,
78 here and on bisphosphonates 7 years followed by a long drug holiday. Had to go back on the bisphosphonates in 2021 and wondered if the drug holiday sort of "reset" things.
Just recently I discovered this Mayo Press article addressing just that; it's from January 2024 so should reflect current thinking.
The paragraph I found interesting follows:
The optimal duration of oral bisphosphonate therapy is typically 5 to 10 years, and for intravenous (IV) bisphosphonates it’s 3 to 6 years. This varies based on your individual fracture risk at one time. Beyond this, a “drug holiday” or withdrawal period is recommended to prevent harmful accumulation of the medicine. After this break, bisphosphonates are often resumed without long-term complications, after proper time lapsed for the natural remodeling process to reset and function normally.
It addressed the length of the holiday later in the article which you can read at:
https://mcpress.mayoclinic.org/healthy-aging/taking-a-break-from-osteoporosis-medicine-what-you-need-to-know/
Oh this sounds somewhat familiar. I am actively seeking a new provider as there are other options that likely could be more helpful. Unfortunately there’s a 4-5 month wait time to get into anyone I’ve tried so far. Or else the ones I’ve selected aren’t taking new patients, and one retired