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Polymyalgia Rheumatica (PMR) | Last Active: Feb 1 4:45am | Replies (41)
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Replies to "Hello @dbloom and @aisp3b I was talking to someone today who apparently has had a flare..."
I've read that 4 am is the peak time for the release of IL-6 and other inflammatory cytokines, so it is best to take prednisone in that time range.
Have you seen this one? It is geared to doctors more so than patients.
https://www.pmrandil6.com/PMRPathophysiologyandIL-6Monograph.pdf