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Using methotrexate with PMR

Polymyalgia Rheumatica (PMR) | Last Active: Feb 3 11:37am | Replies (56)

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@sticksandbugs

I started Methotrexate end of December 2024, and my PMR symptoms are much better but still on 40 mg prednisone daily (no taper) as my inflammatory markers are still high. The Methotrexate side effects are unpleasant though. I was taking weekly folic acid, but have been switched to leucovorin 3-5 days a week depending on severity of side effects. But being able to walk is making me very happy.

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Replies to "I started Methotrexate end of December 2024, and my PMR symptoms are much better but still..."

Saw Rheomatologist today. Going off Methotrexate as of today and back to a little higher Prednisone. Little did I realize until rereading my daily notes that I was gradually getting worse on Methotrexate....no visible side effects....but physically weaker and in more pain. I will be stopping the folic acid and going back to my B12 daily. Hoping to see fast improvement. Hoping to walk a little again!