I took Praluent for about 3 months and then took a statin break when I ruptured my achilles and had a brain bleed from a fall. No way of knowing if statins had an impact on my achilles or just one of those things, but took a break on meds to see where my head was at. Getting back to taking Praluent this week. To answer your question, Praluent was prescribed because I seem to be sensitive to statins and Praluent didn't appear to affect my muscles as of yet. Time may tell.