Mast Cell Activation Disorders or Syndrome (there’s controversy in the field like many others) in general is a body having an overly-enthusiastic response to any substance - food, fabric, fragrance, airborne stuff like pollen or smoke, etc…. and causing a chain reaction “inflammatory response” (akin to the cytokine storm in Covid). If someone has any allergies or sensitivities, this may be an issue.
I’m looking for my fave user-friendly site, but actually Wikipedia is pretty well-rounded.
https://en.wikipedia.org/wiki/Mast_cell_activation_syndrome
There are different classes of mast cells that get activated. The idea is to have mast cell inhibitors “on board” for each class throughout your days. The article lists the classes of inhibitors that you can look through.
Additionally, a table of researched natural supplements is cited:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3764846/table/tbl1/
I hope you or someone will find this helpful. Let me know if you have questions - I’ll keep an eye out.