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@heavyphil

I would like to know what kind of ADT your relatives had that caused their complications and ultimate deaths.
Many of the older types were really estrogen injections, which DO cause cardiovascular events (the older birth control pills were notorious for this). But newer drugs like Orgovyx simply block the production of testosterone - they don’t add estrogen - so whatever estrogen you were producing stays the same.
Of course, an extended stay (years) on any type of ADT can cause issues in some men with predisposing conditions or lead to castrate resistance, but a 6 month or one year course of Orgovyx is not going to kill you and may, in fact, save your life.

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Replies to "I would like to know what kind of ADT your relatives had that caused their complications..."

@heavyphil. Sorry I am not aware of which ADT they were on . Both passed 4 plus years ago .
One was two months shoort of his 90th birthday , Google : Dr. Hamish Small , a distinguished world renouned research scientist . His brothher passed at age 86 . Both were in excellent physical and mental health -- No pre existing issues , And both very active in : walking , golf , cross country sking , kayaking etc . Both surprisingly discontinued having a PSA . Hamish's cancer was diagnosed following a concerning " Alkaline Phosphatase number . Ian , from other indicators and finally a Biopsy . Both were Stage 4 when diagnosed . Both lived less than 2 years after diagnosis .