I have had Migraines since I was 15 years old...that would be 41yrs. except for 1 year while taking Imitrex (in several different forms) then 1 year taking Zomig also in several different forms. At one point I had a stimulator implanted in the back of my head, when I would start having a headache I would activate it and would increase the stimulation. When that began to make my headaches worse I had it and the activator that was implanted in my chest and interfered with my yearly exam. After that the only thing that I found that helped was injections of Demerol & Phenergan up to 3x a month and that helped me for many years. I decided I would try Acupuncture that worked the first time the next 2x made it worse. Botox didn't work ever, it was painful and if I didn't have a headache when I got there I had one when I left. The Demerol/Phenergan was all that worked and then MAYO refused to give narcotics in the Clinic any more and I can't afford the ER co-pay so for 8 years I take Tramadol which gives me slight relief, heat, & Lorazepam and suffer some times for weeks at a time..